Trial Profile

A Randomized, Open, Multicenter Phase III Clinical Trial of Combination of Sintilimab Injection (IBI308) and XELOX+Bevacizumab Compared With XELOX+Bevacizumab as 1st Line Therapy of RAS-Mutant Metastatic Colorectal Cancer

Status: Recruiting

Phase of Trial: Phase III

Latest Information Update: 24 Jun 2025

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At a glance

Drugs Bevacizumab (Primary) ; Capecitabine (Primary) ; Oxaliplatin (Primary) ; Sintilimab (Primary)
Indications Adenocarcinoma; Colorectal cancer
Focus Therapeutic Use

15 Jun 2025 Planned number of patients changed from 494 to 446.
15 Jun 2025 Planned End Date changed from 30 Jun 2025 to 30 Dec 2026.
15 Jun 2025 Planned primary completion date changed from 30 Dec 2024 to 30 Dec 2025.

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