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A Randomized, Open-Label, Multicenter Phase III Study Evaluating Efficacy and Safety of Mosunetuzumab in Combination With Polatuzumab Vedotin in Comparison With Rituximab in Combination With Gemcitabine Plus Oxaliplatin in Participants With Relapsed or Refractory Aggressive B-Cell Non-Hodgkin's Lymphoma

Trial Profile

A Randomized, Open-Label, Multicenter Phase III Study Evaluating Efficacy and Safety of Mosunetuzumab in Combination With Polatuzumab Vedotin in Comparison With Rituximab in Combination With Gemcitabine Plus Oxaliplatin in Participants With Relapsed or Refractory Aggressive B-Cell Non-Hodgkin's Lymphoma

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 15 Apr 2025

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At a glance

  • Drugs Mosunetuzumab (Primary) ; Polatuzumab vedotin (Primary) ; Gemcitabine; Oxaliplatin; Rituximab; Tocilizumab
  • Indications B-cell lymphoma; Diffuse large B cell lymphoma; Follicular lymphoma; Non-Hodgkin's lymphoma
  • Focus Registrational; Therapeutic Use
  • Acronyms SUNMO
  • Sponsors Roche

Most Recent Events

  • 14 Feb 2025 Planned End Date changed from 1 Feb 2027 to 28 Feb 2027.
  • 14 Feb 2025 Planned primary completion date changed from 1 Feb 2025 to 30 May 2025.
  • 19 Sep 2024 Planned End Date changed from 30 Nov 2027 to 1 Feb 2027.

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