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A Phase 3 Randomized, Open-label, Active-comparator Controlled Clinical Study of Pembrolizumab Versus Platinum Doublet Chemotherapy in Participants With Mismatch Repair Deficient (dMMR) Advanced or Recurrent Endometrial Carcinoma in the First-line Setting (KEYNOTE-C93/GOG-3064/ENGOT-en15)

Trial Profile

A Phase 3 Randomized, Open-label, Active-comparator Controlled Clinical Study of Pembrolizumab Versus Platinum Doublet Chemotherapy in Participants With Mismatch Repair Deficient (dMMR) Advanced or Recurrent Endometrial Carcinoma in the First-line Setting (KEYNOTE-C93/GOG-3064/ENGOT-en15)

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 11 Oct 2024

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At a glance

  • Drugs Pembrolizumab (Primary) ; Carboplatin; Cisplatin; Docetaxel; Paclitaxel
  • Indications Carcinoma; Endometrial cancer; Sarcoma
  • Focus Registrational; Therapeutic Use
  • Sponsors Merck Sharp & Dohme; Merck Sharp & Dohme Corp.

Most Recent Events

  • 10 Jun 2024 Planned End Date changed from 17 Jul 2026 to 27 May 2027.
  • 10 Jun 2024 Planned primary completion date changed from 17 Jul 2026 to 27 May 2027.
  • 07 Nov 2023 Status changed from recruiting to active, no longer recruiting.

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