Trial Profile

The Efficacy and Safety of Zanubrutinib, Rituximab and Lenalidomide (ZR2) Versus Rituximab Combined With Low-dose CHOP (R-miniCHOP) in the Treatment of Unfit or Frail de Novo Diffuse Large B-cell Lymphoma Patients Aged Older Than or Equal to 70 Years: A Multicenter, Prospective, Randomized, Open-label, Controlled Trial

Status: Recruiting

Phase of Trial: Phase III

Latest Information Update: 22 Dec 2023

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At a glance

Drugs Lenalidomide (Primary) ; Rituximab (Primary) ; Zanubrutinib (Primary) ; Cyclophosphamide; Doxorubicin; Prednisone; Vincristine
Indications Diffuse large B cell lymphoma
Focus Therapeutic Use
Acronyms The ZR2-Minichop Study

13 Dec 2022 Results (n=21) assessing efficacy and safety in elderly non-GCB DLBCL presented at the 64th American Society of Hematology Annual Meeting and Exposition
17 Jun 2022 Trial design presented at the 27th Congress of the European Haematology Association.
25 Apr 2022 Status changed from not yet recruiting to recruiting.

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