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A Phase IB Study to Assess the Safety and Efficacy of Neoadjuvant Administration of Autologous Tumor Infiltrating Lymphocytes (LN144/Lifileucel) and Pembrolizumab for Treatment of Patients With Locally Advanced (Stage IIIB-D) Melanoma

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Trial Profile

A Phase IB Study to Assess the Safety and Efficacy of Neoadjuvant Administration of Autologous Tumor Infiltrating Lymphocytes (LN144/Lifileucel) and Pembrolizumab for Treatment of Patients With Locally Advanced (Stage IIIB-D) Melanoma

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 13 Jan 2025

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At a glance

  • Drugs Cyclophosphamide (Primary) ; Fludarabine (Primary) ; Lifileucel (Primary) ; Pembrolizumab (Primary)
  • Indications Malignant melanoma
  • Focus Adverse reactions; Therapeutic Use

    • Most Recent Events

    • 08 Jan 2025 Planned End Date changed from 31 Dec 2024 to 31 Dec 2025.
    • 08 Jan 2025 Planned primary completion date changed from 31 Dec 2024 to 31 Dec 2025.
    • 06 Mar 2024 Planned End Date changed from 31 Dec 2025 to 31 Dec 2024.

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