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A Phase 2, Multi-Center, Open-Label, Single-Arm Study to Evaluate the Efficacy and Safety of Lorlatinib Monotherapy in Crizotinib and Platinum-based Chemotherapy Treated Locally Advanced or Metastatic ROS1-Positive Non-Small Cell Lung Cancer Subjects in China

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Trial Profile

A Phase 2, Multi-Center, Open-Label, Single-Arm Study to Evaluate the Efficacy and Safety of Lorlatinib Monotherapy in Crizotinib and Platinum-based Chemotherapy Treated Locally Advanced or Metastatic ROS1-Positive Non-Small Cell Lung Cancer Subjects in China

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 13 Jan 2026

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At a glance

  • Drugs Lorlatinib (Primary)
  • Indications Non-small cell lung cancer
  • Focus Therapeutic Use
  • Sponsors CStone Pharmaceuticals

Most Recent Events

  • 23 Dec 2025 Planned End Date changed from 1 Nov 2025 to 1 May 2026.
  • 30 Jun 2023 Status changed from recruiting to active, no longer recruiting.
  • 31 May 2022 Status changed from not yet recruiting to recruiting.

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