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A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study of Zilovertamab (an ROR1 Antibody) Plus Ibrutinib Versus Ibrutinib Plus Placebo in Subjects With Relapsed or Refractory Mantle Cell Lymphoma

Trial Profile

A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study of Zilovertamab (an ROR1 Antibody) Plus Ibrutinib Versus Ibrutinib Plus Placebo in Subjects With Relapsed or Refractory Mantle Cell Lymphoma

Status: Withdrawn prior to enrolment
Phase of Trial: Phase III

Latest Information Update: 05 Jun 2023

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At a glance

  • Drugs Ibrutinib (Primary) ; Zilovertamab (Primary)
  • Indications Mantle-cell lymphoma
  • Focus Registrational; Therapeutic Use
  • Acronyms ZILO-301
  • Sponsors Oncternal Therapeutics, Inc.

Most Recent Events

  • 04 Jun 2023 This trial as been Discontinued in Spain, According to European Clinical Trials Database record.
  • 26 Apr 2023 This trial has been discontinued in Germany.
  • 19 Apr 2023 Status changed from recruiting to withdrawn prior to enrolment (Due to a strategic reprioritization based on the rapidly changing clinical and commerciallandscape for Bruton's tyrosine kinase inhibitors (BTK inhibitors)

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