A Phase 1b Clinical Study of the Dual MDMX/MDM2 Inhibitor, ALRN-6924, as a Chemoprotection Agent in Patients With TP53-Mutated, HER2 Negative Breast Cancer Receiving Neoadjuvant or Adjuvant Chemotherapy With Docetaxel, Doxorubicin, and Cyclophosphamide (TAC)
Latest Information Update: 24 Jan 2025
At a glance
- Drugs ALRN 6924 (Primary) ; Cyclophosphamide; Docetaxel; Doxorubicin
- Indications Chemotherapy-induced damage
- Focus Adverse reactions
- Sponsors Rein Therapeutics
Most Recent Events
- 10 Jan 2025 According to Rein Therapeutics media release, Aileron Therapeutics announces rebranding to Rein Therapeutics
- 21 Feb 2023 Results presented in an Aileron Therapeutics Media Release.
- 21 Feb 2023 According to an Aileron Therapeutics media release, based on the data from phase 1b breast cancer trial, company decided to terminate the further development of ALRN-6924.