A Randomized and Controlled Phase II Protocol in Non NF1 Pediatric and AYA (Adolescent and Young Adults) Patients Bearing a Newly Diagnosed Low Grade Glioma With Wild Type BRAF Gene Comparing a Daily Oral MEK Inhibitor (Trametinib) Versus Weekly Vinblastine for 18 Months
Latest Information Update: 29 Mar 2024
At a glance
- Drugs Trametinib (Primary) ; Vinblastine
- Indications Astrocytoma; Glioma
- Focus Therapeutic Use
- Acronyms PLGG-MEKTRIC
Most Recent Events
- 07 Jul 2022 Planned End Date changed from 1 Feb 2031 to 1 Dec 2031.
- 07 Jul 2022 Planned primary completion date changed from 1 Jan 2031 to 1 Nov 2031.
- 07 Jul 2022 Status changed from not yet recruiting to recruiting.