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A 52 week study comparing the efficacy and safety of once weekly IcoSema and once weekly semaglutide, both treatment arms with or without oral anti diabetic drugs, in participants with type 2 diabetes inadequately controlled with a GLP 1 receptor agonist. COMBINE 2

Trial Profile

A 52 week study comparing the efficacy and safety of once weekly IcoSema and once weekly semaglutide, both treatment arms with or without oral anti diabetic drugs, in participants with type 2 diabetes inadequately controlled with a GLP 1 receptor agonist. COMBINE 2

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 19 Jan 2025

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At a glance

  • Drugs Insulin-icodec/semaglutide (Primary) ; Semaglutide
  • Indications Type 2 diabetes mellitus
  • Focus Registrational; Therapeutic Use
  • Acronyms COMBINE 2
  • Sponsors Novo Nordisk
  • Most Recent Events

    • 24 Feb 2024 This trial has been completed in Greece (End date:2024-01-16) According European Clinical Trials Database record.
    • 25 Jan 2024 Status changed from active, no longer recruiting to completed.
    • 08 Jan 2024 According to a Novo Nordisk media release, results from this study will be shared later this year.

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