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A Multi-center, Observer-blind, Randomized, Controlled Phase 3 Study to Evaluate the Immunogenicity and Safety of Adjuvanted Recombinant SARS-CoV-2 Trimeric S-protein Subunit Vaccine (SCB-2019), Administered as a Booster Dose to Adults, Who Previously Received Primary Series of a COVID-19 Vaccine

Trial Profile

A Multi-center, Observer-blind, Randomized, Controlled Phase 3 Study to Evaluate the Immunogenicity and Safety of Adjuvanted Recombinant SARS-CoV-2 Trimeric S-protein Subunit Vaccine (SCB-2019), Administered as a Booster Dose to Adults, Who Previously Received Primary Series of a COVID-19 Vaccine

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 28 Aug 2023

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At a glance

  • Drugs SCB 2019 (Primary) ; Ad26.COV2 S; SARS-COV-2 vaccine-inactivated-Sinovac-Biotech; Tozinameran
  • Indications COVID 2019 infections
  • Focus Adverse reactions; Pharmacodynamics; Registrational
  • Sponsors Clover Biopharmaceuticals

Most Recent Events

  • 23 Aug 2023 Status changed from active, no longer recruiting to completed.
  • 13 Jul 2023 Results assessing immunogenicity of Omicron SARS-CoV-2 variants by heterologous SCB-2019 vaccine vs a homologous booster in CoronaVac-primed adults published in the Journal of Infectious Diseases
  • 21 Mar 2023 Status changed from recruiting to active, no longer recruiting.

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