Efficacy and Safety of Zanubrutinib in Combination With R-CHOP in Newly Diagnosed Non-GCB DLBCL Patients With Double Expression: A Single-arm, Open-label, Phase II Study

Status: Active, no longer recruiting

Phase of Trial: Phase II

Latest Information Update: 18 Feb 2025

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At a glance

Drugs Zanubrutinib (Primary) ; Cyclophosphamide; Doxorubicin; Prednisone; Rituximab; Vincristine
Indications Diffuse large B cell lymphoma
Focus Therapeutic Use

16 May 2024 Status changed from recruiting to active, no longer recruiting.
12 Dec 2023 preliminary Results (From Jan 2022 to Jun 2023, n=27) assessing safety and efficacy of Zanubrutinib Combined with R-CHOP in Previously Untreated Non-Germinal Center B-Cell (GCB) Diffuse Large B-Cell Lymphoma (DLBCL) Patients presented at the 65th American Society of Hematology Annual Meeting and Exposition
10 Feb 2022 Status changed from not yet recruiting to recruiting.

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