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RAVEN: A Phase I/II Trial Treating Relapsed Acute Lymphoblastic Leukemia With Venetoclax and Navitoclax

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Trial Profile

RAVEN: A Phase I/II Trial Treating Relapsed Acute Lymphoblastic Leukemia With Venetoclax and Navitoclax

Status: Active, no longer recruiting
Phase of Trial: Phase I/II

Latest Information Update: 06 Nov 2024

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At a glance

  • Drugs Blinatumomab (Primary) ; Calaspargase pegol (Primary) ; Crisantaspase (Primary) ; Crisantaspase (Primary) ; Cyclophosphamide (Primary) ; Cytarabine (Primary) ; Cytarabine (Primary) ; Dasatinib (Primary) ; Dexamethasone (Primary) ; Dexamethasone (Primary) ; Etoposide (Primary) ; Folinic acid (Primary) ; Folinic acid (Primary) ; Hydrocortisone (Primary) ; Mercaptopurine (Primary) ; Methotrexate (Primary) ; Methotrexate (Primary) ; Methotrexate (Primary) ; Navitoclax (Primary) ; Pegaspargase (Primary) ; Pegaspargase (Primary) ; Venetoclax (Primary) ; Vincristine (Primary)
  • Indications Acute biphenotypic leukaemia; Precursor cell lymphoblastic leukaemia-lymphoma
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms RAVEN

    • Most Recent Events

    • 04 Nov 2024 Planned End Date changed from 1 Jul 2029 to 1 Mar 2025.
    • 09 May 2024 Status changed from recruiting to active, no longer recruiting.
    • 06 Mar 2024 Planned number of patients changed from 90 to 98.

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