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A Phase 3 Randomized, Double-Blind, Placebo-Controlled Multicenter, Multinational Study to Evaluate the Efficacy and Safety of Atacicept in Subjects With Active Lupus Nephritis

Trial Profile

A Phase 3 Randomized, Double-Blind, Placebo-Controlled Multicenter, Multinational Study to Evaluate the Efficacy and Safety of Atacicept in Subjects With Active Lupus Nephritis

Status: Withdrawn prior to enrolment
Phase of Trial: Phase III

Latest Information Update: 29 May 2025

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At a glance

  • Drugs Atacicept (Primary)
  • Indications Lupus nephritis; Systemic lupus erythematosus
  • Focus Registrational; Therapeutic Use
  • Acronyms COMPASS
  • Sponsors Vera Therapeutics

Most Recent Events

  • 23 May 2025 Status changed from suspended to withdrawn prior to enrolment.
  • 30 Jun 2023 Status changed from recruiting to suspended.
  • 30 Jan 2023 According to a Vera Therapeutics media release, company plans to prioritize and focus current resources on the advancement of atacicept in IgAN into a pivotal Phase 3 trial, extending cash runway to the fourth quarter of 2024. This updated cash runway guidance assumes a delay in enrollment in this trial.

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