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Multicentric Randomized Phase I/II Study to Evaluate Efficacy of Trifluridine/Tipiracil Plus XB2001 (Anti-IL-1α True Human Antibody) Versus Trifluridine/Tipiracil Plus Placebo in Metastatic Colorectal Cancer Patients After Failure of Oxaliplatin, Irinotecan, Fluoropyrimidine

Trial Profile

Multicentric Randomized Phase I/II Study to Evaluate Efficacy of Trifluridine/Tipiracil Plus XB2001 (Anti-IL-1α True Human Antibody) Versus Trifluridine/Tipiracil Plus Placebo in Metastatic Colorectal Cancer Patients After Failure of Oxaliplatin, Irinotecan, Fluoropyrimidine

Status: Active, no longer recruiting
Phase of Trial: Phase I/II

Latest Information Update: 04 Jun 2025

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At a glance

  • Drugs Tipiracil/trifluridine (Primary) ; Vilamakitug (Primary)
  • Indications Colorectal cancer
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms TASKIN

Most Recent Events

  • 30 May 2025 Status changed from recruiting to active, no longer recruiting.
  • 12 Feb 2024 Planned End Date changed from 1 Mar 2026 to 13 Oct 2026.
  • 12 Feb 2024 Planned primary completion date changed from 1 Mar 2024 to 13 Oct 2026.

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