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A Phase 2 Randomized Study of the BER Inhibitor TRC102 in Combination With Standard Pemetrexed-Platinum-Radiation in Stage III Non-Squamous Non-Small Cell Lung Cancer

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Trial Profile

A Phase 2 Randomized Study of the BER Inhibitor TRC102 in Combination With Standard Pemetrexed-Platinum-Radiation in Stage III Non-Squamous Non-Small Cell Lung Cancer

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 16 Jun 2025

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At a glance

  • Drugs Methoxyamine hydrochloride (Primary) ; Cisplatin; Durvalumab; Pemetrexed
  • Indications Adenocarcinoma; Carcinoma; Non-small cell lung cancer
  • Focus Therapeutic Use

Most Recent Events

  • 10 Jun 2025 Planned End Date changed from 31 Dec 2025 to 30 Jun 2027.
  • 10 Jun 2025 Planned primary completion date changed from 31 Dec 2025 to 30 Jun 2027.
  • 05 Apr 2024 Planned number of patients changed from 78 to 42.

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