Trial Profile

A multicenter, cohort study assessing the potential impact of treatment with inotuzumab ozogamicin on chimeric antigen receptor t-cell therapy in children with relapsed or refractory acute lymphoblastic leukemia

Status: Completed

Phase of Trial: Phase IV

Latest Information Update: 14 Feb 2023

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At a glance

Drugs CAR-T cell therapies (Primary) ; Inotuzumab ozogamicin (Primary) ; Blinatumomab
Indications Precursor B-cell lymphoblastic leukaemia-lymphoma
Focus Therapeutic Use

01 Jan 2023 Results investigated whether prior use of inotuzumab ozogamicin (InO),may impact CAR T-cell manufacturing or efficacy via pre-CART-19 depletion of the B-cell compartment published in the Leukemia
27 Jan 2022 New trial record
14 Dec 2021 Results presented at the 63rd American Society of Hematology Annual Meeting and Exposition

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