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A Modular Phase I/II, Open-label, Dose Escalation and Expansion, Multicentre Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of AZD0466 as Monotherapy or in Combination With Anticancer Agents in Patients With Advanced Non-Hodgkin Lymphoma

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Trial Profile

A Modular Phase I/II, Open-label, Dose Escalation and Expansion, Multicentre Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of AZD0466 as Monotherapy or in Combination With Anticancer Agents in Patients With Advanced Non-Hodgkin Lymphoma

Status: Discontinued
Phase of Trial: Phase I/II

Latest Information Update: 09 Jan 2025

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At a glance

  • Drugs AZD-0466 (Primary)
  • Indications B-cell lymphoma; Diffuse large B cell lymphoma; Follicular lymphoma; Mantle-cell lymphoma; Marginal zone B-cell lymphoma; Non-Hodgkin's lymphoma
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors AstraZeneca; AstraZeneca AB

Most Recent Events

  • 01 Oct 2024 This trial has been completed in France (Global end date: 23 July 2024)
  • 10 Apr 2024 Results assessing safety and efficacy of AZD0466 in patients with advanced non-Hodgkin lymphoma, presented at the 115th Annual Meeting of the American Association for Cancer Research
  • 13 Sep 2023 This trial has been suspended in Spain,according to the European Clinical Trials Database record.

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