Trial Profile

A Phase 1 Study of AMG 176 as Monotherapy and in Combination With Azacitidine in Higher-Risk Myelodysplastic Syndrome and Chronic Myelomonocytic Leukemia

Status: Discontinued

Phase of Trial: Phase I

Latest Information Update: 21 Feb 2025

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At a glance

Drugs Azacitidine (Primary) ; Azacitidine (Primary) ; Tapotoclax (Primary)
Indications Chronic myelomonocytic leukaemia; Myelodysplastic syndromes
Focus Adverse reactions; Therapeutic Use
Sponsors Amgen

Most Recent Events

14 Feb 2025 Status changed from completed to discontinued.
04 Jun 2024 Results(Between 10/2022-12/2023, n=4 pts) studying effects of tapotoclax , presented at the 60th Annual Meeting of the American Society of Clinical Oncology
03 Jan 2024 Status changed from recruiting to completed.

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