A Phase I Trial Evaluating the Safety, Tolerability and Pharmacokinetics of Intravenously Administered M6229 in Critically Ill Sepsis Patients - "HistoSeps"

Status: Completed

Phase of Trial: Phase I

Latest Information Update: 02 Feb 2024

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At a glance

30 Jan 2024 According to a Matisse Pharmaceuticals media release, this study met its primary objectives, showing favorable safety and tolerability as well as close to dose-proportional pharmacokinetics of IV administered M6229 in critically ill patients with sepsis. Further quantitative analyses on plasma histones H3 and H2b are ongoing.
30 Jan 2024 Results presented in a Matisse Pharmaceuticals Media Release.
11 Oct 2023 Status changed from recruiting to completed.

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