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An Open-label, Multicenter , Phase II Clinical Study to Evaluate the Efficacy and Safety of HLX07 ( Recombinant Humanized Anti-EGFR Monoclonal Antibody Injection) Combination Therapy or Monotherapy in Patients With Locally Advanced, Unresectable or Metastatic Esophageal Squamous Cell Carcinoma (ESCC)

Trial Profile

An Open-label, Multicenter , Phase II Clinical Study to Evaluate the Efficacy and Safety of HLX07 ( Recombinant Humanized Anti-EGFR Monoclonal Antibody Injection) Combination Therapy or Monotherapy in Patients With Locally Advanced, Unresectable or Metastatic Esophageal Squamous Cell Carcinoma (ESCC)

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 28 Jun 2023

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At a glance

  • Drugs Cisplatin (Primary) ; Fluorouracil (Primary) ; Pimurutamab (Primary) ; Serplulimab (Primary)
  • Indications Adenosquamous carcinoma; Carcinoma; Oesophageal cancer; Squamous cell cancer
  • Focus Therapeutic Use
  • Sponsors Shanghai Henlius Biotech

Most Recent Events

  • 06 Jun 2023 Results (n=49) assessing efficacy and safety of HLX07, a novel recombinant humanized anti-EGFR monoclonal antibody (mAb), as monotherapy or combination therapy in patients with locally advanced, unresectable/metastatic ESCC presented at the 59th Annual Meeting of the American Society of Clinical Oncology
  • 06 Jun 2023 According to a Shanghai Henlius Biotech media release, this study is lead by was led by Professor Jing Huang from the National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College.
  • 06 Jun 2023 According to a Shanghai Henlius Biotech media release, results from this trial were presented at 2023 American Society of Clinical Oncology (ASCO) Annual Meeting.

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