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Randomized Open-labeled Phase 2 Study of Maintenance Olaparib With or Without Durvalumab for DDR Gene Mutated Advanced Biliary Tract Cancer Following Platinum-based Chemotherapy

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Trial Profile

Randomized Open-labeled Phase 2 Study of Maintenance Olaparib With or Without Durvalumab for DDR Gene Mutated Advanced Biliary Tract Cancer Following Platinum-based Chemotherapy

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 31 Jan 2025

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At a glance

  • Drugs Durvalumab (Primary) ; Olaparib (Primary) ; Platinum complexes
  • Indications Adenocarcinoma; Biliary cancer; Cholangiocarcinoma; Gallbladder cancer
  • Focus Therapeutic Use
  • Acronyms OPTIMUM

Most Recent Events

  • 28 Jan 2025 Planned End Date changed from 30 Dec 2025 to 30 Dec 2026.
  • 28 Jan 2025 Planned primary completion date changed from 30 Dec 2024 to 30 Dec 2025.
  • 15 Jan 2024 Planned End Date changed from 30 Oct 2024 to 30 Dec 2025.

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