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A Phase IIa, Placebo-Controlled, Randomized Study of Daily Obeticholic Acid (OCA) to Reduce Intestinal Polyp Burden in Familial Adenomatous Polyposis (FAP)

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Trial Profile

A Phase IIa, Placebo-Controlled, Randomized Study of Daily Obeticholic Acid (OCA) to Reduce Intestinal Polyp Burden in Familial Adenomatous Polyposis (FAP)

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 18 May 2025

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At a glance

  • Drugs Obeticholic acid (Primary)
  • Indications Familial adenomatous polyposis; Intestinal polyps
  • Focus Therapeutic Use

Most Recent Events

  • 13 Apr 2024 Planned End Date changed from 31 Jan 2026 to 21 Feb 2026.
  • 23 Nov 2023 Planned number of patients changed from 60 to 80.
  • 23 Nov 2023 Planned End Date changed from 21 Feb 2026 to 31 Jan 2026.

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