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A Prospective Observational Sub-Study of the Global Hypophosphatasia Registry to Describe the Potential Risk of Immune-Mediated Loss of Pharmacological Effect of Asfotase Alfa in Participants With Hypophosphatasia

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Trial Profile

A Prospective Observational Sub-Study of the Global Hypophosphatasia Registry to Describe the Potential Risk of Immune-Mediated Loss of Pharmacological Effect of Asfotase Alfa in Participants With Hypophosphatasia

Status: Recruiting
Phase of Trial: Phase IV

Latest Information Update: 06 Mar 2025

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At a glance

  • Drugs Asfotase alfa (Primary)
  • Indications Hypophosphatasia
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Alexion AstraZeneca Rare Disease

Most Recent Events

  • 19 Aug 2024 Planned number of patients changed from 40 to 30.
  • 19 Aug 2024 Planned End Date changed from 30 Jun 2028 to 19 Aug 2029.
  • 19 Aug 2024 Planned primary completion date changed from 30 Jun 2028 to 19 Aug 2029.

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