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A 60 Month, Single-arm, Proof-of-concept Study to Induce Allogeneic Tolerance in Deceased Donor Liver Transplant Recipients Using Siplizumab, an Anti-CD2 Antibody in Combination With Cyclophosphamide and Splenectomy

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Trial Profile

A 60 Month, Single-arm, Proof-of-concept Study to Induce Allogeneic Tolerance in Deceased Donor Liver Transplant Recipients Using Siplizumab, an Anti-CD2 Antibody in Combination With Cyclophosphamide and Splenectomy

Status: Suspended
Phase of Trial: Phase II

Latest Information Update: 10 Aug 2026

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At a glance

  • Drugs Corticosteroids (Primary) ; Cyclophosphamide (Primary) ; Siplizumab (Primary)
  • Indications Liver transplant rejection
  • Focus Proof of concept; Therapeutic Use
  • Sponsors ITBMed Biopharmaceuticals

Most Recent Events

  • 01 Apr 2026 Status changed from active, no longer recruiting to suspended.
  • 25 Nov 2024 Status changed from recruiting to active, no longer recruiting.
  • 17 Feb 2022 New trial record

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