A Randomized, Uncontrolled, Exploratory Phase 2 Trial of Irinotecan Plus Anlotinib or Further in Combination With Penpulimab as Second-line Treatment of Metastatic Colorectal Cancer (ZL-IRIAN)
Latest Information Update: 16 Jul 2024
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At a glance
- Drugs Catequentinib (Primary) ; Irinotecan (Primary) ; Penpulimab (Primary)
- Indications Adenocarcinoma; Colorectal cancer
- Focus Therapeutic Use
- Acronyms ZL-IRIAN
- 02 Jul 2024 Planned End Date changed from 30 Sep 2024 to 31 Dec 2025.
- 02 Jul 2024 Planned primary completion date changed from 31 Mar 2024 to 31 May 2025.
- 04 Jun 2024 Results exploring the rationality of anlotinib plus chemotherapy or further combined with a novel anti-PD-1 IgG1 antibody penpulimab in the second line treatment of mCRC, presented at the 60th Annual Meeting of the American Society of Clinical Oncology