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A Phase 2b Randomized, Double-blind, Active-and Placebo-controlled, Parallel-group, Multicenter Study to Evaluate the Efficacy and Safety of Induction and Maintenance Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Crohn's Disease

Trial Profile

A Phase 2b Randomized, Double-blind, Active-and Placebo-controlled, Parallel-group, Multicenter Study to Evaluate the Efficacy and Safety of Induction and Maintenance Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Crohn's Disease

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 03 Apr 2025

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At a glance

  • Drugs Golimumab/guselkumab (Primary) ; Golimumab; Guselkumab
  • Indications Crohn's disease
  • Focus Therapeutic Use
  • Acronyms DUET-CD
  • Sponsors Janssen Research & Development; Janssen-Cilag
  • Most Recent Events

    • 31 Oct 2024 Planned End Date changed from 6 Jan 2031 to 5 Nov 2029.
    • 11 Sep 2024 Planned End Date changed from 27 Mar 2029 to 6 Jan 2031.
    • 17 Jul 2024 Status changed from recruiting to active, no longer recruiting.

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