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A Phase 1B, Multiple Ascending Dose Trial Examining The Safety And Tolerability Of Subcutaneous MANP In Difficult To Control/Resistant Hypertensive Subjects

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Trial Profile

A Phase 1B, Multiple Ascending Dose Trial Examining The Safety And Tolerability Of Subcutaneous MANP In Difficult To Control/Resistant Hypertensive Subjects

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 28 Mar 2025

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At a glance

  • Drugs M atrial natriuretic peptide (Primary)
  • Indications Resistant hypertension
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors E-Star BioTech

    • Most Recent Events

    • 26 Mar 2025 According to an E-Star BioTech media release, results from this study presented at at the 2025 Annual Meeting of the American College of Cardiology.
    • 26 Mar 2025 Results published in the E-Star BioTech Media Release
    • 08 Oct 2024 According to an E-Star BioTech media release, the support of $36 million in grants and seed-stage private investment, MANP has demonstrated a strong safety profile in multiple Phase 1 studies of participants with Hypertension, Resistant Hypertension, and Hypertension with comorbid Cardiometabolic Syndrome.

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