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A First-in-human, Double-blind, Placebo-controlled, Multicentre, Cross-over, Phase I Study to Assess Safety and Tolerability of Repeat Oral Administrations of MRx0029 OR MRx0005 in Adult Participants With Idiopathic Parkinson's Disease

Trial Profile

A First-in-human, Double-blind, Placebo-controlled, Multicentre, Cross-over, Phase I Study to Assess Safety and Tolerability of Repeat Oral Administrations of MRx0029 OR MRx0005 in Adult Participants With Idiopathic Parkinson's Disease

Status: Withdrawn prior to enrolment
Phase of Trial: Phase I

Latest Information Update: 24 May 2023

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At a glance

  • Drugs CJRB 301 (Primary) ; CJRB 302 (Primary)
  • Indications Parkinson's disease
  • Focus Adverse reactions; First in man
  • Sponsors 4D Pharma PLC

Most Recent Events

  • 31 Mar 2022 According to a 4D Pharma PLC media release, Phase I trial of MRx0005 and MRx0029 in people with Parkinsons disease expected to commence in 2H 2022.
  • 25 Feb 2022 New trial record
  • 22 Feb 2022 According to a 4D Pharma PLC media release, the U.S. Food and Drug Administration (FDA) has cleared investigational new drug (IND) applications for two Live Biotherapeutics (LBPs), MRx0005 and MRx0029, for the treatment of Parkinsons disease.

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