Trial Profile

A Phase II/III Study of Paclitaxel/Carboplatin Alone or Combined With Either Trastuzumab and Hyaluronidase-oysk (HERCEPTIN HYLECTA) or Pertuzumab, Trastuzumab, and Hyaluronidase-zzxf (PHESGO) in HER2 Positive, Stage I-IV Endometrial Serous Carcinoma or Carcinosarcoma

Status: Recruiting

Phase of Trial: Phase III

Latest Information Update: 15 Jun 2025

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At a glance

Drugs Pertuzumab/trastuzumab (Primary) ; Trastuzumab (Primary) ; Carboplatin; Paclitaxel
Indications Adenocarcinoma; Carcinoma; Endometrial cancer; Sarcoma; Uterine cancer
Focus Adverse reactions; Therapeutic Use

27 Mar 2025 Planned number of patients changed from 525 to 360.
22 May 2024 Biospecimen Collection and Computed tomography scans are newly added to the treatments section.
26 Aug 2022 Planned number of patients changed from 326 to 525.

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