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Randomized, Multicenter, Open-label, Phase 3 Study of Mirvetuximab Soravtansine in Combination With Bevacizumab Versus Bevacizumab Alone as Maintenance Therapy for Patients With FRα-high Recurrent Platinum-sensitive Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancers Who Have Not Progressed After Second Line Platinum-based Chemotherapy Plus Bevacizumab (GLORIOSA)

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Trial Profile

Randomized, Multicenter, Open-label, Phase 3 Study of Mirvetuximab Soravtansine in Combination With Bevacizumab Versus Bevacizumab Alone as Maintenance Therapy for Patients With FRα-high Recurrent Platinum-sensitive Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancers Who Have Not Progressed After Second Line Platinum-based Chemotherapy Plus Bevacizumab (GLORIOSA)

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 21 Mar 2025

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At a glance

  • Drugs Bevacizumab (Primary) ; Mirvetuximab soravtansine (Primary)
  • Indications Carcinoma; Fallopian tube cancer; Ovarian cancer; Peritoneal cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms GLORIOSA
  • Sponsors AbbVie

    • Most Recent Events

    • 06 Jun 2023 Trial design presented at the 59th Annual Meeting of the American Society of Clinical Oncology
    • 09 May 2023 According to an Immunogen media release, results from this trial will be presented in an poster presentation at the 2023 American Society of Clinical Oncology (ASCO) Annual Meeting.
    • 16 Dec 2022 Planned initiation date changed from 1 Oct 2022 to 1 Dec 2022.

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