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A Phase 2 double blind, randomized, placebo controlled study evaluating the effect of SAR443820 on serum neurofilament levels in participants with multiple sclerosis, followed by an open label long-term extension period

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Trial Profile

A Phase 2 double blind, randomized, placebo controlled study evaluating the effect of SAR443820 on serum neurofilament levels in participants with multiple sclerosis, followed by an open label long-term extension period

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 17 Dec 2024

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At a glance

  • Drugs Oditrasertib (Primary)
  • Indications Multiple sclerosis
  • Focus Proof of concept; Therapeutic Use
  • Acronyms K2 study
  • Sponsors Sanofi

    • Most Recent Events

    • 06 Nov 2024 Status changed from active, no longer recruiting to discontinued, According to a Denali Therapeutics media release,
    • 06 Nov 2024 According to a Denali Therapeutics media release, this study has been discontinued in October, based on not meeting the primary and key secondary endpoints.
    • 08 Jan 2024 According to a Denali Therapeutics media release, company continue K2 Phase 2 study in MS expected in 2024.

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