Trial Profile

A Multicohort, Open Label, Phase 2 Study of Botensilimab (AGEN1181) for Treatment of Advanced Melanoma Refractory to Prior Checkpoint Inhibitor Therapy

Status: Active, no longer recruiting

Phase of Trial: Phase II

Latest Information Update: 23 Jan 2026

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At a glance

Drugs Balstilimab (Primary) ; Botensilimab (Primary)
Indications Malignant melanoma
Focus Therapeutic Use
Acronyms ACTIVATE- MELANOMA
Sponsors Agenus

Most Recent Events

10 Mar 2025 Planned End Date changed from 1 May 2028 to 1 Feb 2028.
10 Mar 2025 Planned primary completion date changed from 1 May 2028 to 1 Feb 2028.
12 Dec 2024 Status changed from suspended to active, no longer recruiting.

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