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Phase 1 Study of the PKMYT1 Inhibitor RP-6306 in Combination with FOLFIRI for the Treatment of Advanced Solid Tumors

Trial Profile

Phase 1 Study of the PKMYT1 Inhibitor RP-6306 in Combination with FOLFIRI for the Treatment of Advanced Solid Tumors

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 26 Nov 2024

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At a glance

  • Drugs Fluorouracil (Primary) ; Folinic acid (Primary) ; Irinotecan (Primary) ; Lunresertib (Primary)
  • Indications Colorectal cancer; Gastrointestinal cancer; Oesophageal cancer; Solid tumours
  • Focus Adverse reactions
  • Acronyms MINOTAUR
  • Sponsors Repare Therapeutics

Most Recent Events

  • 30 Jun 2024 According to a Repare Therapeutics media release, data from this trial presented at the ESMO GI Cancers Congress in June 2024.
  • 26 Jun 2024 According to a Repare Therapeutics media release, 38 patients were enrolled in the clinical trial as of May 2, 2024, the cutoff date for the data presented at ESMO GI Cancers Congress.
  • 26 Jun 2024 According to a Repare Therapeutics media release, Elisa Fontana, M.D., Ph.D., Medical Director, Sarah Cannon Research Institute UK will be presenting the initial positive results, in a mini oral presentation at the ESMO GI Cancers Congress.

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