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ML43165 - Single Arm Phase 2 Trial of an FDA Approved Anti-CD19 CAR-T Therapy Followed by Mosunetuzumab and Polatuzumab Consolidation for the Treatment of Refractory/Relapsed Aggressive NHL

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Trial Profile

ML43165 - Single Arm Phase 2 Trial of an FDA Approved Anti-CD19 CAR-T Therapy Followed by Mosunetuzumab and Polatuzumab Consolidation for the Treatment of Refractory/Relapsed Aggressive NHL

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 25 Dec 2024

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At a glance

  • Drugs CAR-T cell therapies (Primary) ; Mosunetuzumab (Primary) ; Polatuzumab vedotin (Primary)
  • Indications B-cell lymphoma; Burkitt's lymphoma; Diffuse large B cell lymphoma; Follicular lymphoma; Mantle-cell lymphoma; Non-Hodgkin's lymphoma
  • Focus Therapeutic Use

Most Recent Events

  • 19 Dec 2024 Planned number of patients changed from 40 to 22.
  • 19 Dec 2024 Planned End Date changed from 1 Dec 2027 to 31 Dec 2027.
  • 19 Dec 2024 Planned primary completion date changed from 1 Dec 2025 to 31 Dec 2025.

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