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An open-label dose-escalation study evaluating the safety, pharmacokinetics and antiviral activity of IMC-M113V in HLA-A*02:01 positive subjects with chronic HIV infection who are virologically suppressed

Trial Profile

An open-label dose-escalation study evaluating the safety, pharmacokinetics and antiviral activity of IMC-M113V in HLA-A*02:01 positive subjects with chronic HIV infection who are virologically suppressed

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 12 Mar 2025

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At a glance

  • Drugs IMC-M113V (Primary)
  • Indications HIV-1 infections
  • Focus Adverse reactions; First in man
  • Acronyms STRIVE
  • Sponsors Immunocore

Most Recent Events

  • 12 Mar 2025 According to an Immunocore media release, enrollment in MAD portion of the trial continues with higher doses being evaluated.
  • 10 Mar 2025 Initial data presented in an Immunocore Media Release.
  • 10 Mar 2025 According to an Immunocore media release, initial data from this study presented in an oral session at the Conference on Retroviruses and Opportunistic Infections (CROI) 2025, in San Francisco.

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