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A Phase I, Open-label, Multicenter Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Efficacy of HS-20089 in Patients With Advanced Solid Tumors

Trial Profile

A Phase I, Open-label, Multicenter Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Efficacy of HS-20089 in Patients With Advanced Solid Tumors

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 07 Apr 2024

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At a glance

  • Drugs HS-20089 (Primary)
  • Indications Advanced breast cancer; Endometrial cancer; Male breast cancer; Ovarian cancer; Solid tumours; Triple negative breast cancer
  • Focus Adverse reactions; First in man
  • Sponsors Shanghai Hansoh Biomedical

Most Recent Events

  • 01 Apr 2024 Planned End Date changed from 31 Dec 2023 to 31 Dec 2026.
  • 01 Apr 2024 Planned primary completion date changed from 31 Dec 2023 to 31 Dec 2024.
  • 24 Oct 2023 Results (As of Apr. 11th, 2023, n=44) assessing the dose-limiting toxicity (DLT), safety, tolerability, pharmacokinetics, and efficacy of HS-20089 in patients (pts) with advanced solid tumors refractory to standard therapy presented at the 48th European Society for Medical Oncology Congress

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