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An Adaptive, Randomized, Double-blind, Dose Exploration, Parallel Group, Placebo Controlled, Multicenter Phase 2 Trial to Evaluate the Efficacy, Safety and Tolerability of LNP023 in Combination With Standard-of-care With and Without Oral Corticosteroids in Patients With Active Lupus Nephritis Class III-IV, +/- V

Trial Profile

An Adaptive, Randomized, Double-blind, Dose Exploration, Parallel Group, Placebo Controlled, Multicenter Phase 2 Trial to Evaluate the Efficacy, Safety and Tolerability of LNP023 in Combination With Standard-of-care With and Without Oral Corticosteroids in Patients With Active Lupus Nephritis Class III-IV, +/- V

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 28 Sep 2024

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At a glance

  • Drugs Iptacopan (Primary) ; Corticosteroids
  • Indications Lupus nephritis
  • Focus Therapeutic Use
  • Sponsors Novartis Pharma A.G.; Novartis Pharmaceuticals
  • Most Recent Events

    • 08 Aug 2022 Planned initiation date changed from 2 May 2022 to 1 Aug 2022.
    • 08 Aug 2022 Status changed from not yet recruiting to recruiting.
    • 10 Mar 2022 New trial record

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