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A Phase 1 Single and Multiple Ascending Dose Study to Assess the Safety and Pharmacokinetics of SZN-043, a Novel Bispecific Fusion Protein Targeting ASGR1 and ZNRF3/RNF43, in Healthy Volunteers and Subjects with Liver Cirrhosis

Trial Profile

A Phase 1 Single and Multiple Ascending Dose Study to Assess the Safety and Pharmacokinetics of SZN-043, a Novel Bispecific Fusion Protein Targeting ASGR1 and ZNRF3/RNF43, in Healthy Volunteers and Subjects with Liver Cirrhosis

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 13 Jun 2024

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At a glance

  • Drugs SZN 043 (Primary)
  • Indications Liver cirrhosis
  • Focus Adverse reactions; First in man
  • Sponsors Surrozen

Most Recent Events

  • 10 Jun 2024 Results presented in a Surrozen Media Release.
  • 10 Jun 2024 According to a Surrozen media release, preliminary results of a Phase 1a study of SZN-043 presented on June 8, 2024 at the 2024 European Association for the Study of the Liver (EASL) in Milan.
  • 04 Jun 2024 Status changed from active, no longer recruiting to completed.

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