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An Open-label, Phase I Multicenter, Clinical Trial of NECVAX-NEO1 in Addition to Anti-PD-1 or Anti-PD-L1 Monoclonal Antibody Checkpoint Inhibitor Monotherapy in Patients With Solid Tumors

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Trial Profile

An Open-label, Phase I Multicenter, Clinical Trial of NECVAX-NEO1 in Addition to Anti-PD-1 or Anti-PD-L1 Monoclonal Antibody Checkpoint Inhibitor Monotherapy in Patients With Solid Tumors

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 03 Jul 2025

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At a glance

  • Drugs Oral T-cell immunotherapies-NEC Corporation/VAXIMM (Primary)
  • Indications Head and neck cancer; Malignant melanoma; Non-small cell lung cancer; Renal cell carcinoma; Solid tumours; Squamous cell cancer; Urogenital cancer
  • Focus Adverse reactions; First in man

Most Recent Events

  • 26 Jun 2025 Status changed from recruiting to active, no longer recruiting.
  • 16 May 2024 Planned number of patients changed from 6 to 15.
  • 16 May 2024 Planned primary completion date changed from 31 Dec 2023 to 31 Dec 2025.

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