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A Multicenter Phase 1, Open-Label Trial of Loncastuximab Tesirine in Combination with DA-EPOCH-R in Patients with Previously Untreated Aggressive B-cell Lymphoid Malignancies

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Trial Profile

A Multicenter Phase 1, Open-Label Trial of Loncastuximab Tesirine in Combination with DA-EPOCH-R in Patients with Previously Untreated Aggressive B-cell Lymphoid Malignancies

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 26 Sep 2024

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At a glance

  • Drugs Cyclophosphamide (Primary) ; Doxorubicin (Primary) ; Etoposide (Primary) ; Loncastuximab tesirine (Primary) ; Prednisone (Primary) ; Rituximab (Primary) ; Vincristine (Primary)
  • Indications B-cell lymphoma; Burkitt's lymphoma; Diffuse large B cell lymphoma; Plasmablastic lymphoma
  • Focus Adverse reactions
  • Acronyms LONCA

Most Recent Events

  • 12 Feb 2024 Planned End Date changed from 1 May 2028 to 1 May 2026.
  • 12 Feb 2024 Planned primary completion date changed from 1 May 2027 to 1 May 2026.
  • 03 Feb 2023 Status changed from not yet recruiting to recruiting.

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