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A Pilot Study of Hypoxia as a Potential Resistance Mechanism to PD-1 Checkpoint Blockade Therapy in Neoadjuvant Treatment of Esophageal Squamous Cell Carcinoma (HYPERION)

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Trial Profile

A Pilot Study of Hypoxia as a Potential Resistance Mechanism to PD-1 Checkpoint Blockade Therapy in Neoadjuvant Treatment of Esophageal Squamous Cell Carcinoma (HYPERION)

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 17 Jul 2023

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At a glance

  • Drugs Cisplatin (Primary) ; Paclitaxel (Primary) ; Pembrolizumab (Primary)
  • Indications Carcinoma; Oesophageal cancer; Squamous cell cancer
  • Focus Therapeutic Use
  • Acronyms HYPERION

Most Recent Events

  • 07 Mar 2023 Planned primary completion date changed from 1 Mar 2023 to 1 Sep 2023.
  • 07 Mar 2023 Status changed from not yet recruiting to recruiting.
  • 21 Mar 2022 New trial record

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