Trial Profile

A Phase 3, Randomized, Double-blind Trial of Pembrolizumab (MK-3475) With or Without Lenvatinib (E7080/MK-7902) in Participants With Treatment-naïve, Metastatic Nonsmall Cell Lung Cancer (NSCLC) Whose Tumors Have a Tumor Proportion Score (TPS) Greater Than or Equal to 1% (LEAP-007)

Status: Completed

Phase of Trial: Phase III

Latest Information Update: 09 Apr 2025

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At a glance

08 May 2024 Status changed from active, no longer recruiting to completed.
28 Dec 2023 Results evaluating first-line lenvatinib plus pembrolizumab versus placebo plus pembrolizumab in metastatic NSCLC in the LEAP-007 study (NCT03829332/NCT04676412), published in the Journal of Thoracic Oncology
06 Dec 2023 Planned End Date changed from 30 Nov 2023 to 17 Apr 2024.

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