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A Phase 2 Multicenter, Open-Label, Single-Arm Study to Evaluate the Safety and Efficacy of Oral NRC-2694-A in Combination with Paclitaxel in Patients with Recurrent And/or Metastatic Head and Neck Squamous Cell Carcinoma, Who Progressed on or After Immune Checkpoint Inhibitor Therapy

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Trial Profile

A Phase 2 Multicenter, Open-Label, Single-Arm Study to Evaluate the Safety and Efficacy of Oral NRC-2694-A in Combination with Paclitaxel in Patients with Recurrent And/or Metastatic Head and Neck Squamous Cell Carcinoma, Who Progressed on or After Immune Checkpoint Inhibitor Therapy

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 28 Jan 2025

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At a glance

  • Drugs NRC 2694A (Primary) ; Paclitaxel (Primary)
  • Indications Head and neck cancer; Hypopharyngeal cancer; Laryngeal cancer; Mouth neoplasm; Oropharyngeal cancer; Squamous cell cancer
  • Focus Therapeutic Use
  • Sponsors Natco Pharma

    • Most Recent Events

    • 23 Jan 2025 Planned number of patients changed from 46 to 30.
    • 23 Jan 2025 Planned End Date changed from 2 Jan 2025 to 31 Jan 2026.
    • 23 Jan 2025 Planned primary completion date changed from 31 Dec 2024 to 31 Jan 2026.

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