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A Phase 1/2A, Randomized, Placebo-Controlled, Single-Ascending Dose (Part A, Participant- and Investigator-Blind) and Repeat-Dose (Part B, Participant-, Investigator-, and Sponsor-Blind) Study to Investigate the Safety, Pharmacokinetics, and Efficacy (Part B Only) of UCB1381 in Healthy Study Participants (Part A) and in Study Participants With Moderate to Severe Atopic Dermatitis (Part B)

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Trial Profile

A Phase 1/2A, Randomized, Placebo-Controlled, Single-Ascending Dose (Part A, Participant- and Investigator-Blind) and Repeat-Dose (Part B, Participant-, Investigator-, and Sponsor-Blind) Study to Investigate the Safety, Pharmacokinetics, and Efficacy (Part B Only) of UCB1381 in Healthy Study Participants (Part A) and in Study Participants With Moderate to Severe Atopic Dermatitis (Part B)

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 27 Oct 2025

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At a glance

  • Drugs Donzakimig (Primary) ; Donzakimig (Primary)
  • Indications Atopic dermatitis
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors UCB Biopharma

Most Recent Events

  • 20 Oct 2025 Status changed from active, no longer recruiting to completed.
  • 18 May 2025 Planned End Date changed from 1 Oct 2025 to 22 Sep 2025.
  • 25 Apr 2025 Status changed from recruiting to active, no longer recruiting.

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