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A Randomised, Double-blind, Parallel Group Phase III Study to Assess the Efficacy and Safety of 100 mg SC Depemokimab in Patients With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) - ANCHOR-2 (depemokimAb iN CHrOnic Rhinosinusitis)

Trial Profile

A Randomised, Double-blind, Parallel Group Phase III Study to Assess the Efficacy and Safety of 100 mg SC Depemokimab in Patients With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) - ANCHOR-2 (depemokimAb iN CHrOnic Rhinosinusitis)

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 02 Jun 2025

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At a glance

  • Drugs Depemokimab (Primary)
  • Indications Nasal polyps; Rhinosinusitis
  • Focus Registrational; Therapeutic Use
  • Acronyms ANCHOR-2
  • Sponsors GlaxoSmithKline; GlaxoSmithKline Research & Development; GSK

Most Recent Events

  • 26 May 2025 According to GSK media release, results from this trial have been reported and published in The Lancet.
  • 26 May 2025 According to GSK media release, company announced that it has submitted a New Drug Submission (NDS) to Health Canada for depemokimab. The NDS is based on data from the positive SWIFT and ANCHOR trials.
  • 28 Jan 2025 According to GSK media release, company announced that the European Medicines Agency has accepted for review the Marketing Authorisation Application for the use of depemokimab in two indications based on SWIFT and ANCHOR trials

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