Trial Profile

A Phase 2, Open-label, Study to Evaluate the Safety and Immunogenicity of a Heterologous 2-dose Vaccination Regimen Using Ad26.ZEBOV, MVA-BN-Filo in Adults and Children Originally Enrolled in the Control Arm of the EBOVAC-Salone Study

Status: Completed

Phase of Trial: Phase II

Latest Information Update: 20 May 2025

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At a glance

Drugs Ad26 EBOV vaccine (Primary) ; Modified Vaccinia Ankara Bavarian Nordic Ebola Marburg vaccine (Primary)
Indications Ebola virus infections; Mononegavirales infections
Focus Adverse reactions; Pharmacodynamics

11 May 2025 Status changed from active, no longer recruiting to completed.
14 Aug 2023 Planned End Date changed from 20 Mar 2023 to 31 May 2024.
14 Aug 2023 Planned primary completion date changed from 20 Mar 2023 to 31 Dec 2023.

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