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Exploratory Phase 2A, Double-blind, Placebo-Controlled, Dose Escalation Study to Determine the Safety, Tolerability, PD, and PK of HU6 for the Treatment of Subjects With Obese Heart Failure With Preserved Ejection Fraction (HFpEF)

Trial Profile

Exploratory Phase 2A, Double-blind, Placebo-Controlled, Dose Escalation Study to Determine the Safety, Tolerability, PD, and PK of HU6 for the Treatment of Subjects With Obese Heart Failure With Preserved Ejection Fraction (HFpEF)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 17 Mar 2025

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At a glance

  • Drugs HU 6 (Primary)
  • Indications Diastolic heart failure
  • Focus Pharmacokinetics
  • Acronyms HuMAIN; HuMAIN-HFpEF Trial
  • Sponsors Rivus Pharmaceuticals

Most Recent Events

  • 12 Mar 2025 Results presented in a Rivus Pharmaceuticals Media Release.
  • 12 Mar 2025 According to a Rivus Pharmaceuticals media release, results of this study published in JAMA Cardiology.
  • 30 Sep 2024 According to a Rivus Pharmaceuticals media release, data from this trial were presented by Ambarish Pandey, M.D., a cardiologist and trial investigator, in a Late Breaking Clinical Trial Plenary Session at the Heart Failure Society of America (HFSA) Annual Scientific Meeting 2024 in Atlanta.

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