Trial Profile

A multicenter, phase 1/2, dose-finding and dose expansion study of OSE-279, a PD-1 blocking monoclonal antibody, in subjects with advanced solid tumors or lymphomas

Status: Recruiting

Phase of Trial: Phase I/II

Latest Information Update: 16 Jul 2025

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At a glance

Drugs OSE 2101 (Primary) ; OSE-279 (Primary)
Indications Alveolar soft part sarcoma; Anal cancer; Liver cancer; Lymphoma; Malignant fibrous histiocytoma; Sarcoma; Soft tissue sarcoma; Solid tumours; Squamous cell cancer; Thyroid cancer; Tumour lysis syndrome
Focus Adverse reactions; First in man
Sponsors OSE Immunotherapeutics

Most Recent Events

04 Jul 2025 Planned End Date changed from 1 Dec 2024 to 1 Dec 2029.
04 Jul 2025 Planned primary completion date changed from 1 Oct 2024 to 1 Dec 2029.
19 Jun 2024 Planned number of patients changed from 24 to 55.

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