Trial Profile

CYCLONE 3: A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Abemaciclib in Combination With Abiraterone Plus Prednisone in Men With High-Risk Metastatic Hormone-Sensitive Prostate Cancer

Status: Discontinued

Phase of Trial: Phase III

Latest Information Update: 08 Sep 2025

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At a glance

30 Apr 2024 In Q1 2024, research and development expenses increased 27% to $2.52 billion, or 29% of revenue, driven by higher development expenses for late-stage assets and additional investments in early-stage research, as well as a charge of approximately $75 million in Q1 2024 associated with the termination of the Verzenio prostate cancer program.
30 Apr 2024 Status changed from active, no longer recruiting to discontinued because of futility following an interim analysis.
01 Feb 2024 Status changed from recruiting to active, no longer recruiting.

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